| Discovery of the First Low Nanomolar Liver Receptor Homolog-1 (LRH-1) Agonist |
Xishan Wu,Yan Zhang,Yong Xu |
2019 Dec; |
Journal of Medicinal Chemistry |
| A Concise Total Synthesis of (+)-Paniculatine |
Jian Liu,Sheng Chen,Ningning Li,Fayang G. Qiu |
2019 Aug; |
Advanced Synthesis & Catalysis |
| One-Pot Enantioselective Synthesis of 2-Pyrrolidinone Derivatives Bearing a Trifluoromethylated All-Carbon Quaternary Stereocenter |
Zhuqing Jia,Xiaoyi Hu,Yunlong Zhao,Fayang G. Qiu,Albert S. C. Chan,Junling Zhao |
2019 Dec; |
Organic Letters |
| Rejuvenation of β cells by epigenetic editing |
Wang Tao,Pei Duanqing |
2019 Jan; |
Journal of Clinical Investigation |
| Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide |
Lin-Ping Wu,Davoud Ahmadvand,Junan Su,Arnaldur Hall,Xiaolong Tan,Z. Shadi Farhangrazi,S. Moein Moghimi |
2019 Oct; |
Nature Communications |
| Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition |
Yi Wu,Keshi Chen,Guangsuo Xing,Linpeng Li,Bochao Ma,Zhijuan Hu,Lifan Duan,Xingguo Liu |
2019 Nov; |
Science Advances |
| SNX17 Recruits USP9X to Antagonize MIB1-Mediated Ubiquitination and Degradation of PCM1 during Serum-Starvation-Induced Ciliogenesis |
Pengtao Wang,Jianhong Xia,Leilei Zhang,Shaoyang Zhao,Shengbiao Li,Haiyun Wang,Shan Cheng,Heying Li,Wenguang Yin,Duanqing Pei,Xiaodong Shu |
2019 Oct; |
Cells |
| Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2 |
Vikas Malik,Laura V. Glaser,Dennis Zimmer,Sergiy Velychko,Mingxi Weng,Markus Holzner,Marius Arend,Yanpu Chen,Yogesh Srivastava,Veeramohan Veerapandian,Zahir Shah,Miguel A. Esteban,Huating Wang,Jiekai Chen,Hans R. Sch？ler,Andrew P. Hutchins,Sebastiaan H. Meijsing,Sebastian Pott,Ralf Jauch |
2019 Aug; |
Nature Communications |
| Tbx15 is required for adipocyte browning induced by adrenergic signaling pathway |
Wei Sun,Xuemei Zhao,Zhengqi Wang,Yi Chu,Liufeng Mao,Shaoqiang Lin, Xuefei Gao,Yuna Song,Xiaoyan Hui,Shiqi Jia,Shibing Tang,Yong Xu,Aimin Xu,Kerry Loomes,Cunchuan Wang,Donghai Wu,Tao Nie |
2019 Oct; |
Molecular Metabolism |
| Synergy of NUP98-HOXA10 Fusion Gene and NrasG12D Mutation Preserves the Stemness of Hematopoietic Stem Cells on Culture Condition |
Yong Dong,Chengxiang Xia,Qitong Weng,Tongjie Wang,Fangxiao Hu,KaitaoWang,Xiaofei Liu,Yang Geng,Lijuan Liu,Hongling Wu,Juan Du |
2019 Aug; |
Cells |
| Molecular architecture of lineage allocation and tissue organization in early mouse embryo |
Guangdun Peng,Shengbao Suo,Guizhong Cui,Fang Yu,Ran Wang,Jun Chen,Shirui Chen,Zhiwen Liu,Guoyu Chen,Yun Qian,Patrick P. L. tam,Jing-Dong J. Han,Naihe Jing |
2019 Aug; |
Nature |
| Estrogen-related receptor gamma regulates hepatic triglyceride metabolism through phospholipase A2 G12B |
Longhui Chen,Min Wu,Shengnan Zhang,Wenjuan Tan,Min Guan,Liqiang Feng,Chen Chen,Jun Tao,Ling Chen,Linbing Qu |
2019 Jul; |
FASEB Journal |
| Detection of Novel Mutations Associated with Independent and Cross-resistance to Isoniazid and Protionamide in Mycobacterium tuberculosis Clinical Isolates |
M.M.Islam,Y.Tan,Y.Gao,H.M.A.Hameed,G.Surineni,X.Li,Z.Liu,S.Tan,……,W.W.Yew,J.Liu,N.Zhong,T.Zhang |
2019 Aug; |
Clinical Microbiology and Infection |
| Mesenchymal-epithelial transition in development and reprogramming |
Duanqing Pei,Xiaodong Shu,Ama Gassama-Diagne,Jean Paul Thiery |
2019 Jan; |
Nature Cell Biology |
| Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Jdp2-Jhdm1b-Mkk6-Glis1-Nanog-Essrb-Sall4 |
Bo Wang,Linlin Wu,Dongwei Li,Yuting Liu,Jing Guo,Chen Li,Yuxiang Yao,Yaofeng Wang,Guoqing Zhao,Xiaoshan Wang,Meijun Fu,He Liu,Shangtao Cao,Chuman Wu,Shengyong Yu,Chunhua Zhou,Yue Qin,Junqi Kuang,Jin Ming,Shilong Chu,Xuejie Yang,Ping Zhu,Guangjin Pan,Jiekai Chen,Jing Liu,Duanqing Pei |
2019 Jun; |
Cell Reports |
| Efficient base editing for multiple genes and loci in pigs using base editors |
Jingke Xie,Weikai Ge,Nan Li,Qishuai Liu,Fangbing Chen,Xiaoyu Yang,Xingyun Huang,Zhen Ouyang,Quanjun Zhang,Yu Zhao,Zhaoming Liu,Shixue Gou,Han Wu,Chengdan Lai,Nana Fan,Qin Jin,Hui Shi,Yanhui Liang,Ting Lan,Longquan Quan,Xiaoping Li,Kepin Wang,Liangxue Lai |
2019 Jun; |
Nature Communications |
| Enantioselective Synthesis of 2‐Oxindole Spirofused Lactones and Lactams by Heck/Carbonylative Cylization Sequences: Method Development and Applications |
Huaanzi Hu,Fan Teng,Jian Liu,Weiming Hu,Shuang Luo,Qiang Zhu |
2019 Jul; |
Angewandte Chemie-International Edition |
| Selective C-H or N-H Imidoylative Annulation of 2-(2-Isocyanophenyl)-1H-indoles Leading to Diverse Indole-fused Scaffolds |
Fan Teng,Weiming Hu,Huaanzi Hu,Shuang Luo,Qiang Zhu |
2019 Mar; |
Advanced Synthesis & Catalysis |
| Plasmodium infection inhibits the expansion and activation of MDSCs and Tregs in the tumor microenvironment in a murine Lewis lung cancer model |
Dickson Adah,Yijun Yang,Quan Liu,Kranthi Gadidasu,Zhu Tao,Songlin Yu,Linglin Dai,Xiaofen Li,Siting Zhao,Limei Qin,Li Qin,Xiaoping Chen |
2019 Apr; |
Cell Communication and Signaling |
| Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer |
Yan Zhang,Xishan Wu,Xiaoqian Xue,Chenchang Li,Junjian Wang,Rui Wang,cheng Zhang,Chao Wang,Yudan Shi,Lingjiao Zou,Qiu Li,Zenghong Huang,Xiaojuan Hao,Kerry M. Loomes,Donghai Wu,Hongwu Chen,Jinxin Xu,Yong Xu |
2019 May; |
Journal of Medicinal Chemistry |
| An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis |
Jiao Li,Kaimeng Huang,Gongcheng Hu,Isaac A. Babarinde,Yaoyi Li,Xiaotao Dong,Yu-Sheng Chen,Liping Shang,Wenjing Guo,Junwei Wang,Zhaoming Chen, Andrew P. Hutchins,Yun-Gui Yang,Hongjie Yao |
2019 Apr; |
Nature Communications |
| Total Synthesis of (-)-Daphenylline |
Bo Xu,Bingyang Wang,Wen Xun,Fayang G.Qiu |
2019 Apr; |
Angewandte Chemie-International Edition |
| The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model |
Yang Liu,Yamin Gao,Jianxiong Liu,Yaoju Tan,Zhiyong Liu,Chiranjibi Chhotaray,Huofeng Jiang,Zhili Lu,Gift Chiwala,Shuai Wang,Gaelle Makafe, Md Mahmudul Islam,H. M. Adnan Hameed,Xingshan Cai,Changwei Wang,Xinjie Li,Shouyong Tan,Tianyu Zhang |
2019 Jan; |
Nature Communications |
| Mesothelin is a target of chimeric antigen receptor T cells for treating gastric cancer |
Jiang Lv,Ruocong Zhao,Di Wu, Diwei Zheng,Zhiping Wu,Jingxuan Shi,Xinru Wei,Qiting Wu,Youguo Long,Simiao Lin,Suna Wang,Zhi Wang,Yang Li,Yantao Chen,Qing He,Suimin Chen,Huihui Yao,Zixia Liu,Zhaoyang Tang,Yao Yao,Duanqing Pei,Pentao Liu,Xuchao Zhang,Zhenfeng Zhang,Shuzhong Cui,Ren Chen,Peng Li |
2019 Feb; |
Journal of Hematology & Oncology |
| High-affinity human programmed death-1 ligand-1 variant promotes redirected T cells to kill tumor cells |
Zhaoduan Liang,Yanyan Li,Ye Tiana,Huanling Zhang,Wenxuan Cai,Anan Chen,Lin Chen,Yifeng Bao,Bo Xiang,Heping Kan,Yi Li |
2019 Apr; |
Cancer Letters |
| Resolving Cell Fate Decisions during Somatic Cell Reprogramming by Single-Cell RNA-Seq |
Lin Guo,Lihui Lin,Xiaoshan Wang,Mingwei Gao,hangtao Cao,Yuanbang Mai,Fang Wu,Junqi Kuang,He Liu,Jiaqi Yang,Shilong Chu,Hong Song,Dongwei Li,Yujian Liu,Kaixin Wu,Jiadong Liu,Jinyong Wang,Guangjin Pan,Andrew P.Hutchins,Jing Liu,Duanqing Pei,Jiekai Chen |
2019 Feb; |
Molecular Cell |
| Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells |
Jiangping He, Xiuling Fu, Meng Zhang, Fangfang He, Wenjuan Li, Mazid Md. Abdul,Jianguo Zhou, Li Sun, Chen Chang, Yuhao Li, He Liu, Kaixin Wu1, Isaac A. Babarinde, Qiang Zhuang,Yuin-Han Loh, Jiekai Chen, Miguel A. Esteban,Andrew P.Hutchins |
2019 Jan; |
Nature Communications |
| The Battle between TET Proteins and DNA Methylation for the Right Cell |
Dongwei Li,Jiekai Chen,Duanqing Pei |
2018 Dec; |
Trends in Cell Biology |
| DNAX-activating protein 10 co-stimulation enhances the anti-tumor efficacy of chimeric antigen receptor T cells |
Ruocong Zhao,Lin Cheng,Zhiwu Jiang,Xinru Wei,Baiheng Li,Qiting Wu,Suna Wang,Simiao Lin,Youguo Long,Xuchao Zhangd,Yilong Wud,Xin Due,Duanqing Pei,Pentao Liu,Yangqiu Li,Shuzhong Cui,Yao Yao,Peng Li |
2018 Nov; |
OncoImmunology |
| Polyester based nanovehicles for siRNA delivery |
Zejun Xu,Danyang Wang,Yanqin Cheng,Mingshi Yang,Lin-Ping Wu |
2018 Nov; |
Materials Science & Engineering C-Materials for Biological Applications |
