| SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-kappa B signalling activation |
Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang |
2021 Jul; |
CELL AND BIOSCIENCE |
| Efficient induction of neural progenitor cells from human ESC/iPSCs on Type I Collagen |
Pengfei Liu , Shubin Chen , Yaofeng Wang , Xiaoming Chen, Yiping Guo, Chunhua Liu, Haitao Wang , Yifan Zhao, Di Wu, Yongli Shan , Jian Zhang, Chuman Wu , Dongwei Li, Yanmei Zhang, Tiancheng Zhou , Yaoyu Chen , Xiaobo Liu, Chenxu Li, Lihui Wang, Bei Jia, Jie Liu , Bo Feng, Jinglei Cai,Duanqing Pei |
2021 Mar; |
SCIENCE CHINA-LIFE SCIENCES |
| Nitric oxide-dependent electron transport chain inhibition by the cytochrome bc1 inhibitor and pretomanid combination kills Mycobacterium tuberculosis |
Sheng Zeng, Jingran Zhang, Mingwei Sun, Xiaofei Zhang, Gregory M Cook,Tianyu Zhang |
2021 Aug; |
Antimicrobial Agents and Chemotherapy |
| Icaritin ameliorates hepatic steatosis via promoting fatty acid β-oxidation and insulin sensitivity |
Yue Xiong, Yan Chen, Xinping Huang, Zhen Yang, Jiaye Zhang, Xiaorui Yu , Ji Fang, Jiawang Tao, Kai You, Ziqi Cheng, Shenglin Tan, Yingying Xu, Fang Yuan, Ying Liu, Yuanqi Zhuang, Fan Yang, Yinxiong Li |
2021 Mar; |
Life Sciences |
| SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury |
Anteneh Getachew, Nasir Abbas, Kai You, Zhen Yang, Muzammal Hussain,Xinping Huang, Ziqi Cheng, Shenglin Tan, Jiawang Tao, Xiaorui Yu, Yan Chen,Fan Yang, Tingcai Pan, Yingying Xu, Guosheng Xu, Yuanqi Zhuang, FeiMa Wu,Yinxiong Li |
2021 Apr; |
iScience |
| AP-1 activity is？a？major barrier of？human somatic cell reprogramming |
Yuting Liu, Jiangping He, Ruhai Chen, He Liu, Jocelyn Chen, Yujian Liu, Bo Wang, Lin Guo, Duanqing Pei, Jie Wang, Jing Liu, Jiekai Chen |
2021 Aug; |
Cellular and Molecular Life Sciences |
| Longitudinal Peripheral Blood Transcriptional Analysis Reveals Molecular Signatures of Disease Progression in COVID-19 Patients |
Qihong Yan, Pingchao Li, Xianmiao Ye, Xiaohan Huang, Bo Feng, Tianxing Ji, Zhilong Chen, Feng Li, Yudi Zhang, Kun Luo, Fengjuan Chen, Xiaoneng Mo, Jianhua Wang, Liqiang Feng, Fengyu Hu, Chunliang Lei, Linbing Qu, Ling Chen |
2021 May; |
Journal of Immunology |
| Hypoproliferative human neural progenitor cell xenografts survived extendedly in the brain of immunocompetent rats |
Chunhua Liu, Xiaoyun Wang, Wenhao Huang, Wei Meng, Zhenghui Su, Qi Xing, Heng Shi, Di Zhang, Min Zhou, Yifan Zhao, Haitao Wang, Guangjin Pan, Xiaofen Zhong, Duanqing Pei,Yiping Guo |
2021 Jul; |
Stem Cell Research & Therapy |
| SS18 regulates pluripotent-somatic transition through phase separation |
Junqi Kuang, Ziwei Zhai, Pengli Li, Ruona Shi, Wenjing Guo, Yuxiang Yao, Jing Guo, Guoqing Zhao, Jiangpin He, Shuyang Xu, Chuman Wu, Shengyong Yu, Chunhua Zhou, Linlin Wu, Yue Qin, Baomei Cai, Wei Li, Zichao Wu, Xiaoxi Li, Shilong Chu, Tingting Yang, Bo Wang, Shangtao Cao, Dongwei Li, Xiaofei Zhang, Jiekai Chen, Jing Liu, Duanqing Pei |
2021 Jul; |
Nature Communications |
| Chromatin accessibility dynamics during cell fate reprogramming |
Dongwei Li, Xiaodong Shu, Ping Zhu, Duanqing Pei |
2021 Feb; |
EMBO REPORTS |
| CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I |
Nan Li,Shixue Gou,Jiaowei Wang,Quanjun Zhang,Xingyun Huang,Jingke Xie,Li Li,Qin Jin,Zhen Ouyang,Fangbing Chen,Weikai Ge, Hui Shi,Yanhui Liang,Zhenpeng Zhuang,Xiaozhu Zhao,Meng Lian,Yinghua Ye ,Longquan Quan,Han Wu,Liangxue Lai,Kepin Wang |
2021 Mar; |
Molecular Therapy |
| IL-6 trans-signaling promotes the expansion and anti-tumor activity of CAR T cells |
Zhiwu Jiang, Rui Liao, Jiang Lv, Shanglin Li, Diwei Zheng, Le Qin, Di Wu, Suimin Chen, Youguo Long, Qiting Wu, Suna Wang, Simiao Lin, Xiaohan Huang, Zhaoyang Tang, Pengcheng Shi, Hongsheng Zhou, Qifa Liu, Ruocong Zhao, Yangqiu Li, Yang Jie, Wei Wei, Peilong Lai, Xin Du, Shuzhong Cui, Robert Weinkove, Pentao Liu, Duanqing Pei, Yao Yao, Peng Li |
2021 May; |
Leukemia |
| Mucosal Priming with a Recombinant Influenza A Virus-Vectored Vaccine Elicits T-Cell and Antibody Responses to HIV-1 in Mice |
Jinlin Wang,Tao Shu,Weiqi Deng,Yali Zheng,Min Liao,Xianmiao Ye,Lujie Han,Ping He,Xuehua Zheng,Ting Li,Ying Feng,Fengyu Hu,Pingchao Li,Caijun Sun,Ling Chen,Feng Li,Liqiang Feng |
2021 May; |
Journal of Virology |
| A Live-Attenuated Zika Virus Vaccine with High Production Capacity Confers Effective Protection in Neonatal Mice |
Xianmiao Ye,Xinglong Liu,Tao Shu,Weiqi Deng,Min Liao,Yali Zheng,Xuehua Zheng,Xiaoyan Zhang,Ting Li,Wenxia Fan,Linbing Qu,Ling Chen, Feng Li, Liqiang Feng |
2021 Jun; |
Journal of Virology |
| Discovery and Characterization of Benzimidazole Derivative XY123 as a Potent, Selective, and Orally Available RORγ Inverse Agonist |
Xishan Wu, Hui Shen, Yan Zhang, Chao Wang, Qiu Li , Cheng Zhang, Xiaoxi Zhuang, Chenchang Li, Yudan Shi, Yanli Xing, Qiuping Xiang, Jinxin Xu , Donghai Wu, Jinsong Liu, Yong Xu |
2021 Jun; |
JOURNAL OF MEDICINAL CHEMISTRY |
| Palladium-Catalyzed Enantioselective 7- exo-Trig Carbopalladation/Carbonylation: Cascade Reactions To Achieve Atropisomeric Dibenzo[ b, d]azepin-6-ones |
Huaanzi Hu, Yan Peng, Ting Yu, Sidi Cheng, Shuang Luo, Qiang Zhu |
2021 May; |
organic letters |
| RNA helicase DDX5 acts as a critical regulator for survival of neonatal mouse gonocytes |
Qing Xia, Guizhong Cui , Ye Fan, Xiuqin Wang, Gongcheng Hu, Lisha Wang , Xi Luo, Lele Yang, Qingqing Cai, Kaibiao Xu , Wenjing Guo, Minghui Gao, Yingying Li, Ji Wu , Wei Li, Jiayu Chen 9 , Huayu Qi, Guangdun Peng , Hongjie Yao |
2021 May; |
Cell Proliferation |
| Ultra-short-course and intermittent TB47-containing oral regimens produce stable cure against Buruli ulcer in a murine model and prevent the emergence of resistance for Mycobacterium ulcerans |
Yamin Gao, H M Adnan Hameed, Yang Liu, Lingmin Guo, Cuiting Fang, Xirong Tian, Zhiyong Liu, Shuai Wang , Zhili Lu, Md Mahmudul Islam, Tianyu Zhang |
2021 Mar; |
Acta Pharmaceutica Sinica B |
| Global Profiling of the Lysine Crotonylome in Different Pluripotent States |
Yuan Lv, Chen Bu, Jin Meng, Carl Ward, Giacomo Volpe, Jieyi Hu, Mengling Jiang, Lin Guo , Jiekai Chen, Miguel A Esteban, Xichen Bao, Zhongyi Cheng |
2021 Mar; |
GENOMICS PROTEOMICS & BIOINFORMATICS |
| Generation of UCiPSC-derived neurospheres for cell therapy and its application |
Shuai Li, Huifang Zhao, Xiaobo Han, Bin Ni, Lang He, Omar Mukama, Jean de Dieu Habimana, Zuoxian Lin, Rongqi Huang, Hualin Huang, Chao Tian , Feng Tang, Zhiyuan Li |
2021 Mar; |
Stem Cell Research & Therapy |
| Robust expansion and functional maturation of human hepatoblasts by chemical strategy |
Tingcai Pan, Jiawang Tao , Yan Chen, Jiaye Zhang , Anteneh Getachew, Yuanqi Zhuang, Ning Wang , Yingying Xu, Shenglin Tan, Ji Fang, Fan Yang , Xianhua Lin, Kai You , Yi Gao, Yin-Xiong Li |
2021 Feb; |
Stem Cell Research & Therapy |
| Pyrido[2, 3-d]pyrimidin-7(8H)-ones as new selective orally bioavailable Threonine Tyrosine Kinase (TTK) inhibitors |
Minhao Huang, Yongjun Huang, Jing Guo, Lei Yu, Yu Chang, Xiaolu Wang, Jinfeng Luo, Yanhui Huang, Zhengchao Tu, Xiaoyun Lu, Yong Xu, Zhimin Zhang, Zhang Zhang, Ke Ding |
2021 Feb; |
European journal of medicinal chemistry |
| Rapid visualized assessment of drug efficacy in live mice with a selectable marker-free autoluminescent Klebsiella pneumoniae |
Xirong Tian, Yamin Gao, Shuai Wang, H M Adnan Hameed, Wei Yu, Cuiting Fang, Jingran Zhang, Yaoju Tan, Zhizhong Cao , Ping Guan, Jinxing Hu , Jianxiong Liu, Nanshan Zhong, Tianyu Zhang |
2021 Apr; |
BIOSENSORS & BIOELECTRONICS |
| The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity |
Jiadong Liu, Mingwei Gao, Jiangping He, Kaixin Wu, Siyuan Lin, Lingmei Jin, Yaping Chen, He Liu, Junjie Shi, Xiwei Wang, Lei Chang, Yingying Lin, Yu-Li Zhao, Xiaofei Zhang, Man Zhang, Guan-Zheng Luo, Guangming Wu, Duanqing Pei, Jie Wang, Xichen Bao, Jiekai Chen |
2021 Mar; |
Nature |
| A General Strategy for the Construction of Calyciphylline A-Type Alkaloids: Divergent Total Syntheses of (-)-Daphenylline and (-)-Himalensine A |
Bingyang Wang, Bo Xu, Wen Xun, Yiming Guo , Jing Zhang, Fayang G Qiu |
2021 Apr; |
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION |
| Palladium-Catalyzed Atroposelective Coupling–Cyclization of 2-Isocyanobenzamides to Construct Axially Chiral 2-Aryl- and 2,3-Diarylquinazolinones |
Fan Teng, Ting Yu, Yan Peng, Weiming Hu, Huaanzi Hu, Yimiao He, Shuang Luo, and Qiang Zhu |
2021 Feb; |
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
| ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems |
Jingke Xie,Xingyun Huang,Xia Wang,Shixue Gou,Yanhui Liang,Fangbing Chen,Nan Li,Zhen Ouyang,Quanjun Zhang,Weikai Ge,Qin Jin,Hui Shi,Zhenpeng Zhuang,Xiaozhu Zhao,Meng Lian,Jiaowei Wang,Yinghua Ye,Longquan Quan,Han Wu,Kepin Wang,Liangxue Lai |
2020 Sep; |
BMC Biology |
| Generation of rat blood vasculature and hematopoietic cells in rat-mouse chimeras by blastocyst complementation |
Xiaomin Wang,Hui Shi,Juanjuan Zhou,Qingjian Zou,Quanjun Zhang,Shixue Gou,Pengfei Chen,Lisha Mou,Nana Fan,Yangyang Suo,Zhen Ouyang,Chengdan Lai,Quanmei Yan,Liangxue Lai |
2020 May; |
Journal of Genetics and Genomics |
| In vivo therapeutic effects of affinity-improved-TCR engineered T-cells on HBV-related hepatocellular carcinoma |
Qi Liu,Ye Tian,Yanyan Li,Wei Zhang,Wenxuan Cai,Yaju Liu,Yuefei Ren,Zhaoduan Liang,Peipei Zhou,Yajing Zhang,Yifeng Bao,Yi Li |
2020 Dec; |
Journal for ImmunoTherapy of Cancer |
| Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells |
Yanling Zhu,Tianyu Wang,Jiaming Gu,Ke Huang,Tian Zhang,Zhishuai Zhang,He Liu,Jun Tang,Yuchan Mai,Yanqi Zhang,Yuhang Li,Yashu Feng,Baoqiang Kang,Jinbing Li,Yongli Shan,Qianyu Chen,Jian Zhang,Bing Long, Junwei Wang,Minghui Gao,Di Zhang,Min Zhou,Xiaofen Zhong,Jiekai Chen,Duanqing Pei,Jinfu Nie,Bing Liu,Guangjin Pan |
2020 Dec; |
Cell Discovery |
