| Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD + redox |
Liang Yang,Xiaobing Lin,Haite Tang,Yuting Fan,Sheng Zeng,Lei Jia,Yukun Li,Yanan Shi,Shujing He,Hao Wang,Zhijuan Hu,Xiao Gong,Xiaoyan Liang,Yi Yang,Xingguo Liu |
2020 Sep; |
Aging Cell |
| Sustainable Approach to Azaheterocyclic Acetamides by Decarboxylative Aminoformylation |
Zhenxing Zhang,Chunqi Jia,Xiangtao Kong,Muzammal Hussain,Zhenyu Liu,Wanqing Liang,Ling Jiang,Hao Jiang,Junyan Ma |
2020 Nov; |
ACS Sustainable Chemistry & Engineering |
| NUP98-HOXA10hd fusion protein sustains multi-lineage haematopoiesis of lineage-committed progenitors in transplant setting |
Yong Dong,Kaitao Wang,Qitong Weng,Tongjie Wang,Peiqing Zhou,Xiaofei Liu,Yang Geng,Lijuan Liu,Hongling Wu,Jinyong Wang,Juan Du |
2020 Sep; |
Cell Proliferation |
| Pd-Catalyzed Domino Imidoylation/Heck/C(sp2)-H Cyclization: Isocyanide Relay Strategy toward Tricyclic-Fused Heterocycles Containing an All-Carbon Quaternary Center |
Fan Teng,Yan Peng,Xilong Wang,Weiming Hu,Huaanzi Hu,Yimiao He,Shuang Luo,Qiang Zhu |
2020 Nov; |
Organic Letters |
| Epithelial-Mesenchymal Transition and Metabolic Switching in Cancer: Lessons From Somatic Cell Reprogramming |
Xiaowei Lai,Qian Li,Fang Wu,Jiechun Lin,Jiekai Chen,Hui Zheng,Lin Guo |
2020 Aug; |
Frontiers in Cell and Developmental Biology |
| Mesenchymal Stem Cells Suppress Leukemia via Macrophage-Mediated Functional Restoration of Bone Marrow Microenvironment |
Chengxiang Xia,Tongjie Wang,Hui Cheng,Yong Dong,Qitong Weng,Guohuan Sun,Peiqing Zhou,Kaitao Wang, Xiaofei Liu,Yang Geng,Shihui Ma,Sha Hao,Ling Xu,Yuxian Guan,Juan Du,Xin Du,Yangqiu Li,Xiaofan Zhu,Yufang Shi,Sheng Xu,Demin Wang,Tao Cheng,Jinyong Wang |
2020 Sep; |
Leukemia |
| β-Catenin safeguards the ground state of mouse pluripotency by strengthening the robustness of the transcriptional apparatus |
Meng Zhang,Yiwei Lai,Vladislav Krupalnik,Pengcheng Guo,Xiangpeng Guo,Jianguo Zhou,Yan Xu,Zhijun Yu,Longqi Liu,Ao Jiang,Wenjuan Li,Mazid Md Abdul,Gang Ma,Na Li,Xiuling Fu,Yuan Lv,Mengling Jiang,Muqddas Tariq,Shahzina Kanwal,Hao Liu,Xueting Xu,Hui Zhang,Yinghua Huang,Lulu Wang,Shuhan Chen,Isaac A Babarinde,Zhiwei Luo,Dongye Wang,Tiantian Zhou,Carl Ward,Minghui He,David P Iba？ez,Yunpan Li,Jiajian Zhou, Jie Yuan,Yayan Feng,Karthik Arumugam,Umberto Di Vicino,Xichen Bao,Guangming Wu,Axel Schambach,Huating Wang,Hao Sun,Fei Gao,Baoming Qin,Andrew P Hutchins,Bradley W Doble,Christine Hartmann, Maria Pia Cosma,Yan Qin,Guo-Liang Xu,Runsheng Chen,Giacomo Volpe,Liang Chen,Jacob H Hanna,Miguel A Esteban |
2020 Jul; |
Science Advances |
| JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency |
Yinghua Huang,Hui Zhang,Lulu Wang,Chuanqing Tang,Xiaogan Qin,Xinyu Wu,Meifang Pan,Yujia Tang,Zhongzhou Yang,Isaac A Babarinde,Runxia Lin,Guanyu Ji,Yiwei Lai,Xueting Xu,Jianbin Su,Xue Wen,Takashi Satoh, Tanveer Ahmed,Vikas Malik,Carl Ward,Giacomo Volpe,Lin Guo,Jinlong Chen,Li Sun,Yingying Li,Xiaofen Huang, Xichen Bao,Fei Gao,Baohua Liu,Hui Zheng,Ralf Jauch,Liangxue Lai,Guangjin Pan,Jiekai Chen,Giuseppe Testa,Shizuo Akira,Jifan Hu,Duanqing Pe,Andrew P Hutchin,Miguel A Esteban,Baoming Qin |
2020 Oct; |
Nature Communication |
| Tandem [5 + 2]/[4 + 2] Cycloadditions To Construct the [6-7-6] Tricyclic Skeleton of Icetexane Diterpenes: Total Synthesis of Euolutchuol E, Przewalskine E and Brussonol |
Jing Zhang,Yehua Jin,Fayang G Qiu |
2020 Oct; |
Organic letters |
| YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways |
Jiadong Liu,Mingwei Gao,Shuyang Xu,Yaping Chen,Kaixin Wu,He Liu,Jie Wang,Xuejie Yang,Junwei Wang,Weiwei Liu,Xichen Bao,Jiekai Chen |
2020 Sep; |
Cell Reports |
| Systematic screening of CTCF binding partners identifies that BHLHE40 regulates CTCF genome-wide distribution and long-range chromatin interactions |
Gongcheng Hu,Xiaotao Dong,Shixin Gong,Yawei Song,Andrew P Hutchins,Hongjie Yao |
2020 Sep; |
Nucleic Acids Research |
| Rapid,serial,non-invasive quantification of Pseudomonas aeruginosa in live mice with a selectable marker-free autoluminescent strain |
Shuai Wang,Wei Yu,Zhiyong Liu,Xiaoyin Cai,Sheng Zeng,Jingran Zhang,Yamin Gao,Yaoju Tan,Zhizhong Cao,Lingmin Guo,H.M.Adnan Hameed,Shahzad Akbar Khan,Zafran Khan,Xirong Tian,Cuiting Fang,Md Mahmudul Islam,Sanjeep Sapkota,Ping Guan,Jinxing Hu,Jianxiong Liu,Nanshan Zhong,Tianyu Zhang |
2020 Oct; |
Biosensors & Bioelectronics |
| Perspectives on Somatic Reprogramming: Spotlighting Epigenetic Regulation and Cellular Heterogeneity |
Jiekai Chen |
2020 Oct; |
Current Opinion in Genetics & Development |
| Using Single-Cell and Spatial Transcriptomes to Understand Stem Cell Lineage Specification During Early Embryo Development |
Guangdun Peng,Guizhong Cui,Jincan Ke,Naihe Jing |
2020 Aug; |
Annual Review of Genomics and Human Genetics |
| An ultrasensitive and specific point-of-care CRISPR/Cas12 based lateral flow biosensor for the rapid detection of nucleic acids |
Omar Mukama,Jinghua Wu,Zhiyuan Li,Qiongxin Liang,Zhijian Yi,Xuewen Lu,Yujie Liu,Yumei Liu,Muzammal Hussain,Gaelle Guiewi Makafe,Jiaxin Liu,Ning Xu,Lingwen Zeng |
2020 Jul; |
Biosensors and Bioelectronics |
| Grand challenges in nanomedicine |
Lin-Ping Wu,Danyang Wang,Zibiao Li |
2020 Jan; |
Materials Science & Engineering C-Materials for Biological Applications |
| Metabolic switch and epithelial-mesenchymal transition cooperate to regulate pluripotency |
Hao Sun,Xiao Yang,Lining Liang,Mengdan Zhang,Yuan Li,Jinlong Chen,Fuhui Wang,Tingting Yang,Fei Meng,Xiaowei Lai,Changpeng Li,Jingcai He,Meiai He,Qiaoran Xu，Qian Li,Lilong Lin,Duanqing Pei,Hui Zheng |
2020 Apr; |
EMBO Journal |
| Lack of AKAP3 disrupts integrity of subcellular structure and proteome of mouse sperm and causes male sterility |
Kaibiao Xu,Lele Yang,Lan Zhang,Huayu Qi |
2020 Jan; |
Development |
| R-loops coordinate with SOX2 in regulating reprogramming to pluripotency |
Yaoyi Li,Yawei Song,Wei Xu,Qin Li,Xinxiu Wang,Kuan Li,Juehan Wang,Zicong Liu,Sergiy Velychko,Rong Ye,Qing Xia,Lei Wang,Rong Guo,Xiaotao Dong,Zhikai Zheng,Yushuang Dai,Haojie Li,Mingze Yao,Yuanchao Xue, Hans R. Sch？ler,Qianwen Sun,Hongjie Yao |
2020 Jun; |
Science Advances |
| BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling |
Shengyong Yu,Chunhua Zhou,Shangtao Cao,Jiangping He,Baomei Cai,Kaixin Wu,Yue Qin,Xingnan Huang,Lizhan Xiao,Jing Ye,Shuyang Xu,Wenxiu Xie,Junqi Kuang,Shilong Chu,Jing Guo,He Liu,Wei Pang,Lin Guo,Mengying Zeng,Xiaoshan Wang,Rongping Luo,Chen Li,Guoqing Zhao,Bo Wang,Linlin Wu,Jiekai Chen,Jing Liu,Duanqing Pei |
2020 Jun; |
Nature Cell Biology |
| OPA1-Exon4b Binds to mtDNA D-Loop for Transcriptional and Metabolic Modulation, Independent of Mitochondrial Fusion |
Liang Yang,Haite Tang,Xiaobing Lin,Yi Wu,Sheng Zeng,Yongzhang Pan,Yukun Li,Ge Xiang,Yi-Fang Lin,Shi-Mei Zhuang,Zhiyin Song,Yiguo Jiang,Xingguo Liu |
2020 Apr; |
Frontiers in Cell and Developmental Biology |
| Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response |
Xuefeng Niu,Qihong Yan,Zhipeng Yao,Fan Zhang,Linbing Qu,Chunlin Wang,Chengrui Wang,Hui Lei,Chaoming Chen,Renshan Liang,Jia Luo,Qian Wang,Lingzhai Zhao,Yudi Zhang,Kun Luo,Longyu Wang,Hongkai Wu,Tingting Liu,Pingchao Li,Zhiqiang Zheng,Yee Joo Tan,Liqiang Feng,Zhenhai Zhang,Jian Han,Fuchun Zhang,Ling Chen |
2020 Jan; |
Emerging Microbes & Infections |
| Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2 |
Linlin Hou,Yuanjie Wei,Yingying Lin,Xiwei Wang,Yiwei Lai,Menghui Yin,Yanpu Chen,Xiangpeng Guo,Senbin Wu,Yindi Zhu,Jie Yuan,Muqddas Tariq,Na Li,Hao Sun,Huating Wang,Xiaofei Zhang,Jiekai Chen,Xichen Bao,Ralf Jauch |
2020 Apr; |
Nucleic Acids Research |
| Naloxone regulates the differentiation of neural stem cells via a receptor-independent pathway |
Jinlong Chen,Lining Liang,Yuan Li,Yixin Zhang,Mengdan Zhang,Tingting Yang,Fei Meng,Xiaowei Lai,Changpeng Li,Jingcai He,Meiai He,Qiaoran Xu,Qian Li,Ping‐Yee Law,Horace H. Loh,Duanqing Pei,Hao Sun,Hui Zheng |
2020 Apr; |
FASEB Journal |
| Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway |
Lining Liang,Jinlong Chen,Yuan Li,Xiaowei Lai,Hao Sun,Changpeng Li,Mengdan Zhang,Tingting Yang,Fei Meng,Ping-Yee Law,Horace H. Loh,Hui Zheng |
2020 Mar; |
Cell Reports |
| Topology-dependent, bifurcated mitochondrial quality control under starvation |
Yanshuang Zhou,Qi Long,Hao Wu,Wei Li,Juntao Qi,Yi Wu,Ge Xiang,Haite Tang,Liang Yang,Keshi Chen,Linpeng Li,Feixiang Bao,Heying Li,Yaofeng Wang,Min Li,Xingguo Liu |
2020 Mar; |
Autophagy |
| JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells |
Yongli Shan,Yanqi Zhang,Yuan Zhao,Tianyu Wang,Jingyuan Zhang,Jiao Yao,Ning Ma,Zechuan Liang,Wenhao Huang,Ke Huang,Tian Zhang,Zhenghui Su,Qianyu Chen,Yanling Zhu,Chuman Wu,Tiancheng Zhou,Wei Sun,Yanxing Wei,Cong Zhang,Chenxu Li,Shuquan Su,Baojian Liao,Mei Zhong,Xiaofen Zhong,Jinfu Nie,Duanqing Pei,Guangjin Pan |
2020 Jan; |
Nature Communications |
| SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States |
Kaixin Wu,He Liu,Yaofeng Wang,Jiangping He,Shuyang Xu,Yaping Chen,Junqi Kuang,Jiadong Liu,Lin Guo,Dongwei Li,Ruona Shi,Li Shen,Yangming Wang,Xiaofei Zhang,Jie Wang,Duanqing Pei,Jiekai Chen |
2020 Jan; |
Cell Reports |
| Heterochromatin loosening by the Oct4 linker region facilitates Klf4 binding and iPSC reprogramming |
Keshi Chen,Qi Long,Guangsuo Xing,Tianyu Wang,YiWu,Linpeng Li,Juntao Qi,Yanshuang Zhou,Bochao Ma,Hans R Sch？ler,Jinfu Nie,Duanqing Pei,Xingguo Liu |
2020 Jan; |
EMBO Journal |
| Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors |
Rongqun Guo,Fangxiao Hu,Qitong Weng,Cui Lv,Hongling Wu,Lijuan Liu,Zongcheng Li,Yang Zeng,Zhijie Bai,Mengyun Zhang,Yuting Liu,Xiaofei Liu,Chengxiang Xia,Tongjie Wang,Peiqing Zhou,Kaitao Wang,Yong Dong, Yuxuan Luo,Xiangzhong Zhang,Yuxian Guan,Yang Geng,Juan Du,Yangqiu Li,Yu Lan,Jiekai Chen,Bing Liu,Jinyong Wang |
2020 Jan; |
Cell Research |
