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    • 论文题目 发表年度
    Ligand binding and heterodimerization with retinoid X receptor (RXR) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding 2018 Nov;
    Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming 2018 Dec;
    Polybrene induces neural degeneration by bidirectional Ca2+ influx-dependent mitochondrial and ER-mitochondrial dynamics 2018 Sep;
    BMI1 enables interspecies chimerism with human pluripotent stem cells 2018 Nov;
    Immune Protection of SIV Challenge by PD-1 Blockade During Vaccination in Rhesus Monkeys 2018 Oct;
    Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish 2018 Jul;
    Directed evolution of reprogramming factors by cell selection and sequencing 2018 Aug;
    Diversity among POU transcription factors in chromatin recognition and cell fate reprogramming 2018 May;
    DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1 2018 Jun;
    Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems 2018 Oct;
    Copper-Catalyzed Bromodifluoroacetylation of Alkenes with Ethyl Bromodifluoroacetate 2018 Sep;
    The homeobox transcription factor MSX2 partially mediates the effects of bone morphogenetic protein 4 (BMP4) on somatic cell reprogramming 2018 Sep;
    Cell- and Tissue-Based Proteome Profiling and Dual Imaging of Apoptosis Markers with Probes Derived from Venetoclax and Idasanutlin 2018 Jul;
    An adenovirus serotype 2-vectored ebolavirus vaccine generates robust antibody and cell-mediated immune responses in mice and rhesus macaques 2018 Jun;
    ATAD2 in cancer: a pharmacologically challenging but tractable target 2018 Jan;
    Design,synthesis, and biological evaluation of novel 7-deazapurine nucleoside derivatives as potential anti-dengue virus agents 2018 Jan;
    Design, Synthesis, and Structure-Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5- d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors 2018 Mar;
    Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer 2018 May;
    Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer 2018 Mar;
    Structure-Based Discovery and Optimization of Benzo[d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC).Journal of Medicinal Chemistry 2018 Apr;
    PCGF5 is required for neural differentiation of embryonic stem cells 2018 May;
    Pd-Catalyzed Divergent C(sp2)-H Activation/Cycloimidoylation of 2-Isocyano-2,3-diarylpropanoates 2018 Apr;
    Enantioselective Synthesis of Planar Chiral Pyridoferrocenes via Palladium-Catalyzed Imidoylative Cyclization Reactions 2018 Apr;
    Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency 2018 Apr;
    A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease 2018 May;
    NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming 2018 Apr;
    A divergent and concise total synthesis of (-)-lycoposerramine R and (+)-lycopladine A 2018 Apr;
    Proteome-wide identification of ubiquitin interactions using UbIA-MS 2018 Mar;
    Transcription factor Hoxb5 reprograms B cells into functional T lymphocytes 2018 Mar;
    Capturing the interactome of newly transcribed RNA 2018 Mar;
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