| Enhancing prime editor flexibility with coiled-coil heterodimers |
Shuangshuang Mu,Huangyao Chen,Qianru Li,Shixue Gou,Xiaoyi Liu,Junwei Wang,Wei Zheng, Menglong Chen,Qin Jin,Liangxue Lai,Kepin Wang,Hui Shi |
2024 |
Genome Biology |
| Kupffer cells abrogate homing and repopulation of allogeneic hepatic progenitors in injured liver site |
Nasir Abbas,Kai You,Anteneh Getachew,Feima Wu,Muzammal Hussain,Xinping Huang,Yan Chen,Tingcai Pan,Yinxiong Li |
2024 |
Stem Cell Research & Therapy |
| Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses |
Lu Xue,Tiancai Chang,Zimu Li,Chenchen Wang,Heyu Zhao,Mei Li,Peng Tang,Xin Wen,Mengmeng Yu,Jiqin Wu,Xichen Bao,Xiaojun Wang,Peng Gong,Jun He,Xinwen Chen,Xiaoli Xiong |
2024 |
Nature Communications |
| An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike |
Banghui Liu,Xuefeng Niu,Yijun Deng,Zhaoyong Zhang,Yanqun Wang,Xijie Gao,Huan Liang,Zimu Li,Qian Wang,Yuanyi Cheng,Qiuluan Chen,Shuangshuang Huang,Yingxian Pan,Mengzhen Su,Xiancheng Lin,Chuanying Niu,Yinglin Chen,Wenyi Yang,Yudi Zhang,Qihong Yan,Jun He, Jincun Zhao,Ling Chen,Xiaoli Xiong |
2024 |
Cell Reports |
| A novel protein CYTB-187AA encoded by the mitochondrial gene CYTB modulates mammalian early development |
Zhijuan Hu,Liang Yang,Maolei Zhang,Haite Tang,Yile Huang,Yujie Su,Yingzhe Ding,Chong Li,Mengfei Wang,Yunhao Zhou,Qing Zhang,Liman Guo,Yue Wu,Qianqian Wang,Ning Liu,Haoran Kang,Yi Wu,Deyang Yao, Yukun Li,Zifeng Ruan,Hao Wang,Feixiang Bao,Guopan Liu,Junwei Wang,Yaofeng Wang,Wuming Wang,Gang Lu,Dajiang Qin,Duanqing Pei,Wai-Yee Chan,Xingguo Liu |
2024 |
Cell Metabolism |
| Bispecific CAR-T cells targeting FAP and GPC3 have the potential to treat hepatocellular carcinoma |
Linfu Zhou,Yao Li,Diwei Zheng,Yongfang Zheng,Yuanbin Cui,Le Qin,Zhaoyang Tang,Dongdong Peng,Qiting Wu,Youguo Long,Yao Yao,Nathalie Wong,James Lau,Peng Li |
2024 |
Molecular Therapy-oncolytics |
| CACIMAR: cross-species analysis of cell identities, markers, regulations, and interactions using single-cell RNA sequencing data |
Junyao Jiang,Jinlian Li,Sunan Huang,Fan Jiang,Yanran Liang,Xueli Xu,Jie Wang |
2024 |
Briefings in Bioinformatics |
| Copper/Chiral Phosphoric-Acid-Catalyzed Intramolecular Reductive Isocyanide-Alkene (1 + 2) Cycloaddition: Enantioselective Construction of 2-Azabicyclo[3.1.0]hexanes |
Sidi Cheng,Ting Yu, Jing Li,Yingxiang Liang,Shuang Luo,Qiang Zhu |
2024 |
Journal of the American Chemical Society |
| Enantioselective synthesis of inherently chiral 9-benzylidene-9H-tribenzo[a,c,e][7]annulene and its application as a ligand platform |
Xilong Wang,Chaoqin Wang,Yu Luo,Jing Li,Chunfang Gan,Shuang Luo,Qiang Zhu |
2024 |
Chem Catalysis |
| Inherently chiral azaheterocycles: Asymmetric synthesis via (dynamic) kinetic resolution |
Yu Luo,Shuang Luo,Qiang Zhu |
2024 |
Chem Catalysis |
| Deep immunoglobulin repertoire sequencing depicts a comprehensive atlas of spike-specific antibody lineages shared among COVID-19 convalescents |
Qihong Yan,Yudi Zhang,Ruitian Hou,Wenjing Pan,Huan Liang,Xijie Gao,Weiqi Deng,Xiaohan Huang,Linbing Qu,Congli Tang,Ping He,Banghui Liu,Qian Wang,Xinwei Zhao,Zihan Lin,Zhaoming Chen,Pingchao Li, Jian Han,Xiaoli Xiong,Jincun Zhao,Song Li,Xuefeng Niu,Ling Chen |
2023 |
Emerging Microbes & Infections |
| MicroRNA-200 Loaded Lipid Nanoparticles Promote Intestinal Epithelium Regeneration in Canonical MicroRNA-Deficient Mice |
Xiyang Wei,Shicheng Yu,Tinghong Zhang,Liansheng Liu,Xu Wang,Xiaodan Wang,Yun-Shen Chan,Yangming Wang,Shu Meng,Ye-Guang Chen |
2023 |
ACS Nano |
| A new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine |
Wenming Liu,Hengchun Li,Bo Liu,Tianxing Lv,Chenchen Yang,Si Chen,Liqiang Feng, Liangxue Lai, Ziyuan Duan, Xinwen Chen, Pingchao Li, Suhua Guan, Ling Chen |
2023 |
Emerging Microbes & Infections |
| Evaluation of guide-free Cas9-induced genomic damage and transcriptome changes in pig embryos |
Weikai,Xiaozhu Zhao,Shixue Gou,Qin Jin, Fangbing Chen,Zhen Ouyang,Chengdan Lai,Tao Cui,Baoyi Mai,Sijia Lu,Kexin Zhong,Yanhui Liang,Tao Chen,Han Wu,Nan Li,Yinghua Ye,Liangxue Lai,Kepin Wang |
2023 |
Molecular Therapy Nucleic Acids |
| Unraveling the 2,3-diketo-L-gulonic acid-dependent and -independent impacts of L-ascorbic acid on somatic cell reprogramming |
Lining Liang,Meiai He,Yixin Zhang,Chenchen Wang,Zhaohui Qin,Qian Li,Tingting Yang,Fei Meng,Yusheng Zhou,Haofei Ge,Weining Song,Shiyu Chen,Linna Dong,Qiwen Ren,Changpeng Li,Lin Guo,Hao Sun,Wei Zhang,Duanqing Pei,Hui Zheng |
2023 |
Cell and Bioscience |
| BCL11B and the NuRD complex cooperatively guard T-cell fate and inhibit OPA1-mediated mitochondrial fusion in T cells |
Rui Liao,Yi Wu,Le Qin,Zhiwu Jiang,Shixue Gou,Linfu Zhou,Qilan Hong,Yao Li,Jingxuan Shi,Yao Yao,Liangxue Lai,Yangqiu Li,Pentao Liu,Jean Paul Thiery,Dajiang Qin,Thomas Graf,Xingguo Liu,Peng Li |
2023 |
The EMBO Journal |
| Simultaneous profiling of spatial gene expression and chromatin accessibility during mouse brain development |
Fuqing Jiang,Xin Zhou,Yingying Qian,Miao Zhu,Li Wang,Zhuxia Li,Qingmei Shen,Minhan Wang,Fangfang Qu,Guizhong Cui,Kai Chen,Guangdun Peng |
2023 |
Nature Methods |
| Transforming Growth Factor Beta Promotes Inflammation and Tumorigenesis in Smad4-Deficient Intestinal Epithelium in a YAP-Dependent Manner |
Liansheng Liu,Yalong Wang,Shicheng Yu,Huidong Liu,Yehua Li,Shan Hua,Ye-Guang Chen |
2023 |
Advanced Science |
| T lymphocytes expressing the switchable chimeric Fc receptor CD64 exhibit augmented persistence and antitumor activity |
Yuanbin Cui,Tingjie Yuan,Ying Wang,Diwei Zheng,Le Qin,Shanglin Li,Zhiwu Jiang,Shouheng Lin,Wenjing Guo,Zhi Wang,Zhaoduan Liang,Yi Li,Yao Yao,Xingguo Liu,Qiannan Tang,Hai-Yan Tu,Xu-Chao Zhang, Zhaoyang Tang,Nathalie Wong,Zhenfeng Zhang,Dajiang Qin,Jean Paul Thiery,Kailin Xu,Peng Li |
2023 |
Cell Reports |
| A Rationally Designed CRISPR/Cas12a Assay Using a Multimodal Reporter for Various Readouts |
Jean de Dieu Habimana,Omar Mukama,Obed Boadi Amissah,Yirong Sun,Eric Karangwa,Yujie Liu,Samson Mugisha,Na Cheng,Ling Wang,Jianlin Chen,Sihao Deng,Rongqi Huang,Zhiyuan Li |
2023 |
Analytical Chemistry |
| Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex |
Shuqi Dong,Huadong Li,Meilin Wang,Nadia Rasheed,Binqian Zou,Xijie Gao,Jiali Guan,Weijie Li,Jiale Zhang,Chi Wang,Ningkun Zhou,Xue Shi,Mei Li,Min Zhou,Junfeng Huang,He Li,Ying Zhang,Koon Ho Wong,Xiaofei Zhang,William Chong Hang Chao,Jun He |
2023 |
Cell Research |
| Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription |
Jingke Xie,Zhenpeng Zhuang,Shixue Gou,Quanjun Zhang,Xia Wang,Ting Lan,Meng Lian,Nan Li,Yanhui Liang,Zhen Ouyang,Yinghua Ye,Han Wu,Liangxue Lai,Kepin Wang |
2023 |
Nucleic Acids Research |
| Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation |
Jiaowei Wang,Wenguang Xie,Nan Li,Wenjuan Li,Zhishuai Zhang,Nana Fan,Zhen Ouyang,Yu Zhao,Chengdan Lai,Hao Li,Mengqi Chen,Longquan Quan,Yunpan Li,Yu Jiang,Wenqi Jia,Lixin Fu,Md. Abdul Mazid, Yanling Zhu,Patrick H. Maxwel,Guangjin Pan,Miguel A. Esteban,Zhen Dai,Liangxue Lai |
2023 |
Cell Stem Cell |
| Nuclear localization of TET2 requires β-catenin activation and correlates with favourable prognosis in colorectal cancer |
Changpeng Li,Jingcai He,Fei Meng,Fuhui Wang,Hao Sun,Huizhong Zhang,Linna Dong,Mengdan Zhang,Qiaoran Xu,Lining Liang,Yuan Li,Tingting Yang,Meiai He,Tao Wang,Jiechun Lin,Jiaqi Sun,Qiuling Huang, Lin Guo,Xiaofei Zhang,Shijuan Mai,Hui Zheng |
2023 |
Cell Death & Disease |
| Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte |
Shiting Zhao,Tao Nie,Lei Li,Qiaoyun Long,Ping Gu,Yuwei Zhang,Wei Sun,Zexin Lin,Qing Liu,Yue Qi,Wei Wang,Mengyuan Xie,Kerry Loomes,Chenleng Cai,Donghai Wu,Hannah Xiaoyan Hui |
2023 |
Advanced Science |
| 1-Benzyloxy-5-phenyltetrazole derivatives highly active against androgen receptor-dependent prostate cancer cells |
Shiting Zhao,Abdelsalam S Ali,Xinyu Kong,Yan Zhang,Xiaomin Liu,Melissa A Skidmore,Craig M Forsyth,G Paul Savage,Donghai Wu,Yong Xu,Craig L Francis |
2023 |
European Journal of Medicinal Chemistry |
| DEP2: an upgraded comprehensive analysis toolkit for quantitative proteomics data |
Zhenhuan Feng,Peiyang Fang,Hui Zheng,Xiaofei Zhang |
2023 |
Bioinformatics |
| MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy |
Xue Shi, Wenfeng Wu, Zhenhuan Feng, Peiyang Fan, Ruona Shi, Xiaofei Zhang |
2023 |
Cell Reports |
| SARS-CoV-2 induces cardiomyocyte apoptosis and inflammation but can be ameliorated by ACE inhibitor Captopril |
Xiaohan Huang,Wenxia Fan,Jing Sun,Jiaqing Yang,Yanjun Zhang,Qian Wang？Pingchao Li,Yudi Zhang,Shengnan Zhang,Heying Li,Jianhua Wang,Liqiang Feng,Jincun Zhao,Ling Chen,Linbing Qu |
2023 |
Antiviral Research |
| Rational Design, Synthesis and Biological Evaluation of Benzo[d]isoxazole Derivatives as Potent BET Bivalent Inhibitors for Potential Treatment of Prostate Cancer |
Junhua Li, Run Zhu, Xiaoxi Zhuang, Cheng Zhang, Hui Shen, Xishan Wu, Maofeng Zhang, Cen Huang, Qiuping Xiang, Linxiang Zhao, Yong Xu, Yan Zhang |
2023 |
Bioorganic Chemistry |
