| Rapid,serial,non-invasive quantification of Pseudomonas aeruginosa in live mice with a selectable marker-free autoluminescent strain |
Shuai Wang,Wei Yu,Zhiyong Liu,Xiaoyin Cai,Sheng Zeng,Jingran Zhang,Yamin Gao,Yaoju Tan,Zhizhong Cao,Lingmin Guo,H.M.Adnan Hameed,Shahzad Akbar Khan,Zafran Khan,Xirong Tian,Cuiting Fang,Md Mahmudul Islam,Sanjeep Sapkota,Ping Guan,Jinxing Hu,Jianxiong Liu,Nanshan Zhong,Tianyu Zhang |
2020 Oct; |
Biosensors & Bioelectronics |
| Perspectives on Somatic Reprogramming: Spotlighting Epigenetic Regulation and Cellular Heterogeneity |
Jiekai Chen |
2020 Oct; |
Current Opinion in Genetics & Development |
| Using Single-Cell and Spatial Transcriptomes to Understand Stem Cell Lineage Specification During Early Embryo Development |
Guangdun Peng,Guizhong Cui,Jincan Ke,Naihe Jing |
2020 Aug; |
Annual Review of Genomics and Human Genetics |
| An ultrasensitive and specific point-of-care CRISPR/Cas12 based lateral flow biosensor for the rapid detection of nucleic acids |
Omar Mukama,Jinghua Wu,Zhiyuan Li,Qiongxin Liang,Zhijian Yi,Xuewen Lu,Yujie Liu,Yumei Liu,Muzammal Hussain,Gaelle Guiewi Makafe,Jiaxin Liu,Ning Xu,Lingwen Zeng |
2020 Jul; |
Biosensors and Bioelectronics |
| Grand challenges in nanomedicine |
Lin-Ping Wu,Danyang Wang,Zibiao Li |
2020 Jan; |
Materials Science & Engineering C-Materials for Biological Applications |
| Metabolic switch and epithelial-mesenchymal transition cooperate to regulate pluripotency |
Hao Sun,Xiao Yang,Lining Liang,Mengdan Zhang,Yuan Li,Jinlong Chen,Fuhui Wang,Tingting Yang,Fei Meng,Xiaowei Lai,Changpeng Li,Jingcai He,Meiai He,Qiaoran Xu，Qian Li,Lilong Lin,Duanqing Pei,Hui Zheng |
2020 Apr; |
EMBO Journal |
| Lack of AKAP3 disrupts integrity of subcellular structure and proteome of mouse sperm and causes male sterility |
Kaibiao Xu,Lele Yang,Lan Zhang,Huayu Qi |
2020 Jan; |
Development |
| R-loops coordinate with SOX2 in regulating reprogramming to pluripotency |
Yaoyi Li,Yawei Song,Wei Xu,Qin Li,Xinxiu Wang,Kuan Li,Juehan Wang,Zicong Liu,Sergiy Velychko,Rong Ye,Qing Xia,Lei Wang,Rong Guo,Xiaotao Dong,Zhikai Zheng,Yushuang Dai,Haojie Li,Mingze Yao,Yuanchao Xue, Hans R. Sch？ler,Qianwen Sun,Hongjie Yao |
2020 Jun; |
Science Advances |
| BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling |
Shengyong Yu,Chunhua Zhou,Shangtao Cao,Jiangping He,Baomei Cai,Kaixin Wu,Yue Qin,Xingnan Huang,Lizhan Xiao,Jing Ye,Shuyang Xu,Wenxiu Xie,Junqi Kuang,Shilong Chu,Jing Guo,He Liu,Wei Pang,Lin Guo,Mengying Zeng,Xiaoshan Wang,Rongping Luo,Chen Li,Guoqing Zhao,Bo Wang,Linlin Wu,Jiekai Chen,Jing Liu,Duanqing Pei |
2020 Jun; |
Nature Cell Biology |
| OPA1-Exon4b Binds to mtDNA D-Loop for Transcriptional and Metabolic Modulation, Independent of Mitochondrial Fusion |
Liang Yang,Haite Tang,Xiaobing Lin,Yi Wu,Sheng Zeng,Yongzhang Pan,Yukun Li,Ge Xiang,Yi-Fang Lin,Shi-Mei Zhuang,Zhiyin Song,Yiguo Jiang,Xingguo Liu |
2020 Apr; |
Frontiers in Cell and Developmental Biology |
| Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response |
Xuefeng Niu,Qihong Yan,Zhipeng Yao,Fan Zhang,Linbing Qu,Chunlin Wang,Chengrui Wang,Hui Lei,Chaoming Chen,Renshan Liang,Jia Luo,Qian Wang,Lingzhai Zhao,Yudi Zhang,Kun Luo,Longyu Wang,Hongkai Wu,Tingting Liu,Pingchao Li,Zhiqiang Zheng,Yee Joo Tan,Liqiang Feng,Zhenhai Zhang,Jian Han,Fuchun Zhang,Ling Chen |
2020 Jan; |
Emerging Microbes & Infections |
| Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2 |
Linlin Hou,Yuanjie Wei,Yingying Lin,Xiwei Wang,Yiwei Lai,Menghui Yin,Yanpu Chen,Xiangpeng Guo,Senbin Wu,Yindi Zhu,Jie Yuan,Muqddas Tariq,Na Li,Hao Sun,Huating Wang,Xiaofei Zhang,Jiekai Chen,Xichen Bao,Ralf Jauch |
2020 Apr; |
Nucleic Acids Research |
| Naloxone regulates the differentiation of neural stem cells via a receptor-independent pathway |
Jinlong Chen,Lining Liang,Yuan Li,Yixin Zhang,Mengdan Zhang,Tingting Yang,Fei Meng,Xiaowei Lai,Changpeng Li,Jingcai He,Meiai He,Qiaoran Xu,Qian Li,Ping‐Yee Law,Horace H. Loh,Duanqing Pei,Hao Sun,Hui Zheng |
2020 Apr; |
FASEB Journal |
| Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway |
Lining Liang,Jinlong Chen,Yuan Li,Xiaowei Lai,Hao Sun,Changpeng Li,Mengdan Zhang,Tingting Yang,Fei Meng,Ping-Yee Law,Horace H. Loh,Hui Zheng |
2020 Mar; |
Cell Reports |
| Topology-dependent, bifurcated mitochondrial quality control under starvation |
Yanshuang Zhou,Qi Long,Hao Wu,Wei Li,Juntao Qi,Yi Wu,Ge Xiang,Haite Tang,Liang Yang,Keshi Chen,Linpeng Li,Feixiang Bao,Heying Li,Yaofeng Wang,Min Li,Xingguo Liu |
2020 Mar; |
Autophagy |
| JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells |
Yongli Shan,Yanqi Zhang,Yuan Zhao,Tianyu Wang,Jingyuan Zhang,Jiao Yao,Ning Ma,Zechuan Liang,Wenhao Huang,Ke Huang,Tian Zhang,Zhenghui Su,Qianyu Chen,Yanling Zhu,Chuman Wu,Tiancheng Zhou,Wei Sun,Yanxing Wei,Cong Zhang,Chenxu Li,Shuquan Su,Baojian Liao,Mei Zhong,Xiaofen Zhong,Jinfu Nie,Duanqing Pei,Guangjin Pan |
2020 Jan; |
Nature Communications |
| SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States |
Kaixin Wu,He Liu,Yaofeng Wang,Jiangping He,Shuyang Xu,Yaping Chen,Junqi Kuang,Jiadong Liu,Lin Guo,Dongwei Li,Ruona Shi,Li Shen,Yangming Wang,Xiaofei Zhang,Jie Wang,Duanqing Pei,Jiekai Chen |
2020 Jan; |
Cell Reports |
| Heterochromatin loosening by the Oct4 linker region facilitates Klf4 binding and iPSC reprogramming |
Keshi Chen,Qi Long,Guangsuo Xing,Tianyu Wang,YiWu,Linpeng Li,Juntao Qi,Yanshuang Zhou,Bochao Ma,Hans R Sch？ler,Jinfu Nie,Duanqing Pei,Xingguo Liu |
2020 Jan; |
EMBO Journal |
| Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors |
Rongqun Guo,Fangxiao Hu,Qitong Weng,Cui Lv,Hongling Wu,Lijuan Liu,Zongcheng Li,Yang Zeng,Zhijie Bai,Mengyun Zhang,Yuting Liu,Xiaofei Liu,Chengxiang Xia,Tongjie Wang,Peiqing Zhou,Kaitao Wang,Yong Dong, Yuxuan Luo,Xiangzhong Zhang,Yuxian Guan,Yang Geng,Juan Du,Yangqiu Li,Yu Lan,Jiekai Chen,Bing Liu,Jinyong Wang |
2020 Jan; |
Cell Research |
| Discovery of the First Low Nanomolar Liver Receptor Homolog-1 (LRH-1) Agonist |
Xishan Wu,Yan Zhang,Yong Xu |
2019 Dec; |
Journal of Medicinal Chemistry |
| A Concise Total Synthesis of (+)-Paniculatine |
Jian Liu,Sheng Chen,Ningning Li,Fayang G. Qiu |
2019 Aug; |
Advanced Synthesis & Catalysis |
| One-Pot Enantioselective Synthesis of 2-Pyrrolidinone Derivatives Bearing a Trifluoromethylated All-Carbon Quaternary Stereocenter |
Zhuqing Jia,Xiaoyi Hu,Yunlong Zhao,Fayang G. Qiu,Albert S. C. Chan,Junling Zhao |
2019 Dec; |
Organic Letters |
| Rejuvenation of β cells by epigenetic editing |
Wang Tao,Pei Duanqing |
2019 Jan; |
Journal of Clinical Investigation |
| Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide |
Lin-Ping Wu,Davoud Ahmadvand,Junan Su,Arnaldur Hall,Xiaolong Tan,Z. Shadi Farhangrazi,S. Moein Moghimi |
2019 Oct; |
Nature Communications |
| Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition |
Yi Wu,Keshi Chen,Guangsuo Xing,Linpeng Li,Bochao Ma,Zhijuan Hu,Lifan Duan,Xingguo Liu |
2019 Nov; |
Science Advances |
| SNX17 Recruits USP9X to Antagonize MIB1-Mediated Ubiquitination and Degradation of PCM1 during Serum-Starvation-Induced Ciliogenesis |
Pengtao Wang,Jianhong Xia,Leilei Zhang,Shaoyang Zhao,Shengbiao Li,Haiyun Wang,Shan Cheng,Heying Li,Wenguang Yin,Duanqing Pei,Xiaodong Shu |
2019 Oct; |
Cells |
| Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2 |
Vikas Malik,Laura V. Glaser,Dennis Zimmer,Sergiy Velychko,Mingxi Weng,Markus Holzner,Marius Arend,Yanpu Chen,Yogesh Srivastava,Veeramohan Veerapandian,Zahir Shah,Miguel A. Esteban,Huating Wang,Jiekai Chen,Hans R. Sch？ler,Andrew P. Hutchins,Sebastiaan H. Meijsing,Sebastian Pott,Ralf Jauch |
2019 Aug; |
Nature Communications |
| Tbx15 is required for adipocyte browning induced by adrenergic signaling pathway |
Wei Sun,Xuemei Zhao,Zhengqi Wang,Yi Chu,Liufeng Mao,Shaoqiang Lin, Xuefei Gao,Yuna Song,Xiaoyan Hui,Shiqi Jia,Shibing Tang,Yong Xu,Aimin Xu,Kerry Loomes,Cunchuan Wang,Donghai Wu,Tao Nie |
2019 Oct; |
Molecular Metabolism |
| Synergy of NUP98-HOXA10 Fusion Gene and NrasG12D Mutation Preserves the Stemness of Hematopoietic Stem Cells on Culture Condition |
Yong Dong,Chengxiang Xia,Qitong Weng,Tongjie Wang,Fangxiao Hu,KaitaoWang,Xiaofei Liu,Yang Geng,Lijuan Liu,Hongling Wu,Juan Du |
2019 Aug; |
Cells |
| Molecular architecture of lineage allocation and tissue organization in early mouse embryo |
Guangdun Peng,Shengbao Suo,Guizhong Cui,Fang Yu,Ran Wang,Jun Chen,Shirui Chen,Zhiwen Liu,Guoyu Chen,Yun Qian,Patrick P. L. tam,Jing-Dong J. Han,Naihe Jing |
2019 Aug; |
Nature |
