| A single-dose circular RNA vaccine preventsZika virus infection without enhancing dengue severity in mice |
Xinglong Liu,Zhengfeng Li,Xiaoxia Li,Weixuan Wu,Huadong Jiang,Yufen Zheng,Junjie Zhou,Xianmiao Ye,Junnan Lu,Wei Wang,Lei Yu,Yiping Li,Linbing Qu,Jianhua Wang,Feng Li,Ling Chen,Linping Wu, Liqiang Fen |
2024 |
Nature Communication |
| METTL3/METTL14 maintain human nucleoli integrity by mediating SUV39H1/H2 degradation |
Yongli Shan,Yanqi Zhang,Yanxing Wei,Cong Zhang,Huaisong Lin,Jiangping He,Junwei Wang,Wenjing Guo,Heying Li,Qianyu Chen,Tiancheng Zhou,Qi Xing,Yancai Liu,Jiekai Chen,Guangjin Pan |
2024 |
Nature Communications |
| Hydrophobic core evolution of major histocompatibility complex class I chain-related protein a for dramatic enhancing binding affinity |
Wenxuan Cai,Siqi Peng,Ye Tian,Yifeng Bao,Qiang Liu,Yan Dong,Zhaoduan Liang,Qi Liu, Yuefei Ren,Peng Ding,Jinsong Liu,Tingting Xu,Yi Li |
2024 |
International Journal of Biological Macromolecules |
| YIPF2 regulates genome integrity |
Xiao Zhang,Tao Wang |
2024 |
Cell and Bioscience |
| Perturbation of METTL1-mediated tRNA N7- methylguanosine modification induces senescence and aging |
Yudong Fu,Fan Jiang,Xiao Zhang,Yingyi Pan,Rui Xu,Xiu Liang,Xiaofen Wu,Xingqiang Li,Kaixuan Lin,Ruona Shi,Xiaofei Zhang,Dominique Ferrandon,Jing Liu,Duanqing Pei,Jie Wang,Tao Wang |
2024 |
Nature Communications |
| In vivo evaluation of guide-free Cas9-induced safety risks in a pig model |
Weikai Ge,Shixue Gou,Xiaozhu Zhao,Qin Jin,henpeng Zhuang,Yu Zhao,Yanhui Liang,Zhen Ouyang,Xiaoyi Liu,Fangbing Chen,Hui Shi,Haizhao Yan,Han Wu,Liangxue Lai,Kepin Wang |
2024 |
Signal Transduction and Targeted Therapy |
| NAD+ dependent UPRmt activation underlies intestinal aging caused by mitochondrial DNA mutations |
Liang Yang,Zifeng Ruan,Xiaobing Lin,Hao Wang,Yanmin Xin,Haite Tang,Zhijuan Hu,Yunhao Zhou,Yi Wu,Junwei Wang,Dajiang Qin,Gang Lu,Kerry M Loomes,Wai-Yee Chan,Xingguo Liu |
2024 |
Nature Communications |
| Microbiome-induced reprogramming in post-transcriptional landscape using Nanopore direct RNA sequencing |
Zihe Xu,Xiaoqi Zheng,Jiajun Fan,Yuting Jiao,Sihao Huang,Yingyuan Xie,Shunlan Xu,Yi Lu,Anrui Liu,Runzhou Liu,Ying Yang,Guan-Zheng Luo,Tao Pan,Xiaoyun Wang |
2024 |
Cell Reports |
| Comparison of seven CD19 CAR designs in engineering NK cells for enhancing anti-tumour activity |
Yao Wang,Jianhuan Li,Zhiqian Wang,Yanhong Liu,Tongjie Wang,Mengyun Zhang,Chengxiang Xia,Fan Zhang,Dehao Huang,Leqiang Zhang,Yaoqin Zhao,Lijuan Liu,Yanping Zhu,Hanmeng Qi,Xiaofan Zhu,Wenbin Qian,Fangxiao Hu,Jinyong Wang |
2024 |
Cell Proliferation |
| Discovery and pharmacological characterization of 1,2,3,4-tetrahydroquinoline derivatives as RORγ inverse agonists against prostate cancer |
Xi-Shan Wu,Xiao-Yu Luo,Cheng-Chang Li,Xiao-Fan Zhao,Cheng Zhang,Xiao-Shan Chen,Zhi-Fang Lu,Tong Wu,Hao-Nan Yu,Chao Peng,Qing-Qing Hu,Hui Shen,Yong Xu,Yan Zhang |
2024 |
Acta Pharmacologica Sinica |
| Variant PRC1 subunit RYBP/YAF2 forms condensate with RING1B and promotes H2AK119ub deposition |
Yanjiang Liu,Gongcheng Hu,Shengxiong Yang,Chenghong Yan,Juehan Wang,Guangjin Pan,Hongjie Yao |
2024 |
Science China-Life Sciences |
| Selecting Monoclonal Cell Lineages from Somatic Reprogramming Using Robotic-Based Spatial-Restricting Structured Flow |
Xueping Chen,Ke Fan,Jun Lu,Sheng Zhang,Jianhua Dong,Jisheng Qin,Weihua Fan,Yan Wang,Yiyuan Zhang,Huo Peng,Zhizhong Zhang,Zhiyong Sun,Chunlai Yu,Yucui Xiong,Yan Song,Qingqing Ye,Shiwen Mai,Yuanhua Wang,Qizheng Wang,Fengxiang Zhang,Xiaohui Wen, Tiancheng Zhou,Li Han,Mian Long,Guangjin Pan,Julian F Burke,Xiao Zhang |
2024 |
Research |
| Discovery of highly potent and efficient CBP/p300 degraders with strong in vivo antitumor activity |
Jiankang Hu,Hongrui Xu,Tianbang Wu,Cheng Zhang,Hui Shen,Ruibo Dong,Qingqing Hu,Qiuping Xiang,Shuang Chai,Guolong Luo,Xiaoshan Chen,Yumin Huang,Xiaofan Zhao,Chao Peng,Xishan Wu,Bin Lin,Yan Zhang,Yong Xu |
2024 |
Journal of Medicinal Chemistry |
| Mast cell degranulation-triggered by SARS-CoV-2 induces tracheal-bronchial epithelial inflammation and injury |
Jian-Bo Cao,Shu-Tong Zhu,Xiao-Shan Huang,Xing-Yuan Wang,Meng-Li Wu,Xin-Li,Feng-Liang Liu,Ling Chen,Yong-Tang Zheng,Jian-Hua Wang |
2024 |
Virologica Sinica |
| CTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment |
Jie Zhang,Gongcheng Hu,Yuli Lu,Huawei Ren,Yin Huang,Yulin Wen,Binrui Ji,Diyang Wang, Haidong Wang,Huisheng Liu,Ning Ma, Lingling Zhang,Guangjin Pan,Yibo Qu,Hua Wang,Wei Zhang,Zhichao Miao, Hongjie Yao |
2024 |
Nature Communications |
| Autophagy is essential for human myelopoiesis |
Jiaming Gu,Yanling Zhu,Huaisong Lin,Yuhua Huang,Yanqi Zhang,Qi Xing,Baoqiang Kang,Zhishuai Zhang,Mingquan Wang,Tiancheng Zhou,Yuchan Mai,Qianyu Chen,Fei Li,Xing Hu,Shuoting Wang,Jiaojiao Peng, Xinrui Guo,Bing Long,Junwei Wang,Minghui Gao,Yongli Shan,Yazhou Cui,Guangjin Pan |
2024 |
Stem Cell Reports |
| HBO1 determines SMAD action in pluripotency and mesendoderm specification |
Cong Zhang,Yongli Shan,Huaisong Lin,Yanqi Zhang,Qi Xing,Jinmin Zhu,Tiancheng Zhou, Aiping Lin,Qianyu Chen,Junwei Wang,Guangjin Pan |
2024 |
Nucleic Acids Research |
| Redox-modulated SNX25 as a novel regulator of GPCR-G protein signaling from endosomes |
Yulong Zhang,Zhijun Yu,Mingwei Sun,Ruyue Du,Hanhan Gao,Qiankun Dai,Yan Dong,Cuicui Liu,Menghui Yin,Tingting Xu,Xiaofei Zhang,Jinsong Liu,Jinxin Xu |
2024 |
Redox Biology |
| NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route |
Obed Boadi Amissah,Wenfang Chen,Jean de Dieu Habimana,Yirong Sun,Lihui Lin,Yujie Liu,Ling Wang,Zhaoming Liu,Omar Mukama,Rajesh Basnet,Hohua Liu,Junyi Li,Xuanyan Ding,Lingshuang Lv,Min Chen,Yalin Liang,Rongqi Huang,Zhiyuan Li |
2024 |
Cancer Cell International |
| Enhancing prime editor flexibility with coiled-coil heterodimers |
Shuangshuang Mu,Huangyao Chen,Qianru Li,Shixue Gou,Xiaoyi Liu,Junwei Wang,Wei Zheng, Menglong Chen,Qin Jin,Liangxue Lai,Kepin Wang,Hui Shi |
2024 |
Genome Biology |
| Kupffer cells abrogate homing and repopulation of allogeneic hepatic progenitors in injured liver site |
Nasir Abbas,Kai You,Anteneh Getachew,Feima Wu,Muzammal Hussain,Xinping Huang,Yan Chen,Tingcai Pan,Yinxiong Li |
2024 |
Stem Cell Research & Therapy |
| Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses |
Lu Xue,Tiancai Chang,Zimu Li,Chenchen Wang,Heyu Zhao,Mei Li,Peng Tang,Xin Wen,Mengmeng Yu,Jiqin Wu,Xichen Bao,Xiaojun Wang,Peng Gong,Jun He,Xinwen Chen,Xiaoli Xiong |
2024 |
Nature Communications |
| An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike |
Banghui Liu,Xuefeng Niu,Yijun Deng,Zhaoyong Zhang,Yanqun Wang,Xijie Gao,Huan Liang,Zimu Li,Qian Wang,Yuanyi Cheng,Qiuluan Chen,Shuangshuang Huang,Yingxian Pan,Mengzhen Su,Xiancheng Lin,Chuanying Niu,Yinglin Chen,Wenyi Yang,Yudi Zhang,Qihong Yan,Jun He, Jincun Zhao,Ling Chen,Xiaoli Xiong |
2024 |
Cell Reports |
| A novel protein CYTB-187AA encoded by the mitochondrial gene CYTB modulates mammalian early development |
Zhijuan Hu,Liang Yang,Maolei Zhang,Haite Tang,Yile Huang,Yujie Su,Yingzhe Ding,Chong Li,Mengfei Wang,Yunhao Zhou,Qing Zhang,Liman Guo,Yue Wu,Qianqian Wang,Ning Liu,Haoran Kang,Yi Wu,Deyang Yao, Yukun Li,Zifeng Ruan,Hao Wang,Feixiang Bao,Guopan Liu,Junwei Wang,Yaofeng Wang,Wuming Wang,Gang Lu,Dajiang Qin,Duanqing Pei,Wai-Yee Chan,Xingguo Liu |
2024 |
Cell Metabolism |
| Bispecific CAR-T cells targeting FAP and GPC3 have the potential to treat hepatocellular carcinoma |
Linfu Zhou,Yao Li,Diwei Zheng,Yongfang Zheng,Yuanbin Cui,Le Qin,Zhaoyang Tang,Dongdong Peng,Qiting Wu,Youguo Long,Yao Yao,Nathalie Wong,James Lau,Peng Li |
2024 |
Molecular Therapy-oncolytics |
| CACIMAR: cross-species analysis of cell identities, markers, regulations, and interactions using single-cell RNA sequencing data |
Junyao Jiang,Jinlian Li,Sunan Huang,Fan Jiang,Yanran Liang,Xueli Xu,Jie Wang |
2024 |
Briefings in Bioinformatics |
| Copper/Chiral Phosphoric-Acid-Catalyzed Intramolecular Reductive Isocyanide-Alkene (1 + 2) Cycloaddition: Enantioselective Construction of 2-Azabicyclo[3.1.0]hexanes |
Sidi Cheng,Ting Yu, Jing Li,Yingxiang Liang,Shuang Luo,Qiang Zhu |
2024 |
Journal of the American Chemical Society |
| Enantioselective synthesis of inherently chiral 9-benzylidene-9H-tribenzo[a,c,e][7]annulene and its application as a ligand platform |
Xilong Wang,Chaoqin Wang,Yu Luo,Jing Li,Chunfang Gan,Shuang Luo,Qiang Zhu |
2024 |
Chem Catalysis |
| Inherently chiral azaheterocycles: Asymmetric synthesis via (dynamic) kinetic resolution |
Yu Luo,Shuang Luo,Qiang Zhu |
2024 |
Chem Catalysis |
| Deep immunoglobulin repertoire sequencing depicts a comprehensive atlas of spike-specific antibody lineages shared among COVID-19 convalescents |
Qihong Yan,Yudi Zhang,Ruitian Hou,Wenjing Pan,Huan Liang,Xijie Gao,Weiqi Deng,Xiaohan Huang,Linbing Qu,Congli Tang,Ping He,Banghui Liu,Qian Wang,Xinwei Zhao,Zihan Lin,Zhaoming Chen,Pingchao Li, Jian Han,Xiaoli Xiong,Jincun Zhao,Song Li,Xuefeng Niu,Ling Chen |
2023 |
Emerging Microbes & Infections |
